Panama Canal cruises

Cruise offers on sale now, with ships, departure dates and prices. Choose a line or region to narrow the list.

15 on sale

Celebrity Summit Panama Canal Cruise - L.A. to Boston - 19 Nights

Puerto Vallarta · Celebrity Cruises · Celebrity Summit

17 Sep 2027 – 7 Oct 2027

£1,979

Brilliant Adult Only Panama Canal Cruise From L.A. to Miami- 18 Nights

Cabo San Lucas · Virgin Voyages · Brilliant Lady

26 Nov 2027 – 15 Dec 2027

£2,469

Celebrity Summit Panama Canal Cruise - Tampa to L.A. 16 Nights

Grand Cayman (Cayman Islands) · Celebrity Cruises · Celebrity Summit

17 Apr 2027 – 4 May 2027

£2,599

Brilliant Adult Only Panama Canal Cruise From Miami to L.A.- 17 Nights

Cartagena · Virgin Voyages · Brilliant Lady

20 Feb 2028 – 9 Mar 2028

£2,669

Panama Canal Cruise from Miami to Seattle - 20 Nights

Cartagena · MSC Cruises · MSC Poesia

6 Apr 2027 – 27 Apr 2027

£2,749

Grand Caribbean & Panama Canal Taster All-Inclusive Cruise from Miami

Miami · Norwegian Cruise Line · Norwegian Jewel

7 Dec 2027 – 21 Dec 2027

£2,879

The Joy of the Panama Canal from Miami to L.A.

Cartagena · Norwegian Cruise Line · Norwegian Joy

20 Apr 2027 – 7 May 2027

£2,889

Panama Canal Encore from Los Angeles to Miami- 17 Night Package

Cabo San Lucas · Norwegian Cruise Line · Norwegian Encore

7 Jan 2028 – 25 Jan 2028

£3,019

13 Night Miami Beach, Caribbean ABC Islands and Panama Cruise Package

Miami · Celebrity Cruises · Celebrity Ascent

21 Nov 2026 – 5 Dec 2026

£3,219

Panama Canal Encore from Miami to Los Angeles - 16 Night Package

Cartagena · Norwegian Cruise Line · Norwegian Encore

23 Jan 2028 – 9 Feb 2028

£3,249

Panama Canal Bliss from Los Angeles to Miami- 19 Night Package

Cabo San Lucas · Norwegian Cruise Line · Norwegian Bliss

17 Oct 2027 – 6 Nov 2027

£3,329

Panama Canal Joy from Los Angeles to Miami- 19 Night Package

Cabo San Lucas · Norwegian Cruise Line · Norwegian Joy

28 Sep 2027 – 18 Oct 2027

£3,449

Panama Canal Bliss from New York to San Francisco

Puerto Plata · Norwegian Cruise Line · Norwegian Bliss

12 Apr 2028 – 6 May 2028

£3,579

Signature Panama Canal Cruise Luxury from Miami to Peru

Key West · Oceania Cruises · Insignia

17 Dec 2026 – 4 Jan 2027

£5,989

Andes and Panama Canal All-Inclusive Voyage from Chile to Miami

Santiago · Azamara Cruises · Azamara Journey

8 Mar 2027 – 30 Mar 2027

£10,589